Tag Archives: endometriosis treatment

New drug trial to test endometriosis treatment

Endometriosis treatmentPharmaceutical companies Abbott Laboratories and its partner Neurocrine Biosciences have begun a late-stage trial of their endometriosis treatment drug, elagolix.

The firms have announced a 24-week Phase III trial of elagolix, an oral gonadotropin-releasing hormone (GnRH) antagonist that will be tested in 875 women from 18-49 years old, with moderate to severe endometriosis associated pain. It will be conducted at around 160 sites in North America.

The trial and exploration of the effectiveness of elagolix is an important step in finding potential treatments for this underserved patient population. Phase III trial has begun screening for enrollment and a second late-stage study is being planned. The firm hopes to file a New Drug Application in 2016.

Abbott earned rights to elagolix in June 2010 and the deal could be worth $575 million. It has been estimated that 100 million women worldwide suffer from endometriosis, which is associated with a multitude of symptoms. Some of the most common include pain related both to menstruation as well as chronic pelvic pain throughout the menstrual cycle, and is a leading cause of infertility.

Abbott also noted that the annual costs of endometriosis are estimated to exceed $20 billion in the USA alone.

IVF NY offers online consultations to couples who may be having difficulty conceiving as a result of ineffective endometriosis treatment.

Natural endometriosis treatment eases pain

Endometriosis treatmentEndometriosis refers to when the tissue that lines the uterus, called the endometrium, implants and grows in areas it shouldn’t. This wandering tissue sometimes bleeds and/or secretes into the surrounding tissue when a woman gets her period resulting in cramps and pain wher the tissue has implanted, which could be outside the uterus, the ovaries, fallopian tubes, bladder, or bowel. Symptoms may include the painful periods and bowel movements and lower back pain. Endometriosis treatment is available, but there are more natural ways to help ease the pain. They include:

  1. Eat fish. Consume more fish high in omega-3 fatty acids such as mackerel, salmon, and tuna. A diet high in fish oil can help reduce the endometriosis pain. Opt for fish oil capsules, taken according to the dosage on the label.
  2. Modify meat eating. Red meat is high in arachidonic acid, and leads to tissue inflammation. Eat at least 2 cups of vegetables such as broccoli and cauliflower a day, along with 20 to 50 grams of soy protein. Try to have ½ cup of cooked whole grains such as barley or brown ice.
  3. Use heat pad. Place a warm heating pad on your abdomen. Keep the temperature warm, and use the pad as long as you need to. For safety, place a cloth between the pad and your skin.
  4. Exercise. Evidence suggests that women who exercise are less likely to have endometriosis. If you are in too much pain for vigorous exercise, try strength training, riding a stationary bike.
  5. Get your B vitamins. It is recommended to take a multivitamin supplement that contains 50 to 100 milligrams of each of the B vitamins. The B vitamins can help your liver process estrogen more effectively.
  6. Less dairy. 
Cut back on processed dairy foods such as milk, cheese, and yogurt. Non-organic dairy foods increase estrogen levels, and that increase can intensify the pain.

Endometriosis and infertility are linked, so using these methods, as well as consulting your physician can help reduce discomfort and aid in fertility.